Bivalent genes are regulated by a balance between repressive Polycomb group proteins and activating trithorax group proteins. A new study has revealed that MENIN, an accessory component of KMT2A/B methyltransferase complexes, has an unorthodox role in repressing bivalent genes, alongside Polycomb repressive complexes.

中文翻译：

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剖析二价基因调控中的 MENIN

二价基因受抑制性 Polycomb 组蛋白和激活三胸组蛋白之间的平衡调节。一项新研究表明，MENIN 是 KMT2A/B 甲基转移酶复合物的辅助成分，与 Polycomb 抑制复合物一起，在抑制二价基因方面具有非正统的作用。