Cell death is a mystery in various forms. Whichever type of cell death, this is always accompanied by active or passive molecules release. The recent years marked the renaissance of the study of these molecules showing they can signal to and communicate with recipient cells and regulate physio- or pathological events. This review summarizes the defined forms of messages cells could spread while dying, the effects of these signals on the target tissue/cells, and how these types of communications regulate physio- or pathological processes. By doing so, this review hopes to identify major unresolved questions in the field, formulate new hypothesis worthy of further investigation, and when possible, provide references for the search of novel diagnostic/therapeutics agents.

中文翻译：

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幽灵信息：细胞死亡信号传播

细胞死亡是各种形式的谜。无论哪种类型的细胞死亡，总是伴随着主动或被动分子的释放。近年来标志着这些分子研究的复兴，表明它们可以向受体细胞发出信号并与之通信，并调节生理或病理事件。这篇综述总结了细胞在死亡时可能传播的定义形式的信息、这些信号对目标组织/细胞的影响，以及这些类型的通信如何调节生理或病理过程。通过这样做，本综述希望确定该领域尚未解决的主要问题，提出值得进一步研究的新假设，并在可能的情况下为寻找新型诊断/治疗药物提供参考。