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Evading the Toll booth: How “silent” flagellins may bind yet fail to activate TLR5
Science Immunology ( IF 17.6 ) Pub Date : 2023-01-20 , DOI: 10.1126/sciimmunol.adf0244
Hannah M Baer 1, 2 , Shruti Sandilya 1 , Theodore S Steiner 1
Affiliation  

The nature of flagellin–Toll-like receptor 5 (TLR5) interactions, depending on binding to and activation of TLR5, may hold a key to the distinct differences in gut microbiome and intestinal immune function in different populations around the world (see related Research Article by Clasen et al .).

中文翻译:

逃避收费站:“沉默”的鞭毛蛋白如何结合但无法激活 TLR5

鞭毛蛋白-Toll 样受体 5 (TLR5) 相互作用的性质取决于 TLR5 的结合和激活,这可能是世界各地不同人群肠道微生物组和肠道免疫功能明显差异的关键(参见相关研究文章通过克拉森等人.).
更新日期:2023-01-20
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