Premature ovarian failure is a to some extent unknown and intricate problem with diverse causes and clinical manifestations. The lack of ovarian sex hormones presumably is effective in the occurrence of ovarian failure. Our progress in this field has been very little despite undertaken scientific research endeavors; scholars still are trying to understand the explanation of this dilemmatic medical condition. In contrast, the practice of clinical medicine has made meaningful strides in providing assurance to the women with premature ovarian insufficiency that their quality of life as well as long-term health can be optimized through timely intervention. Very recently Scientists have investigated the regulating effects of small RNA molecules on steroidogenesis apoptosis, ovulation, gonadal, and corpus luteum development of ovaries. In this literature review, we tried to talk over the mechanisms of miRNAs in regulating gene expression after transcription in the ovary.

中文翻译：

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miRNAs 干扰卵巢功能和卵巢早衰的作用

卵巢早衰在某种程度上是一个未知且复杂的问题，具有多种原因和临床表现。卵巢性激素的缺乏可能会导致卵巢功能衰竭的发生。尽管进行了科学研究，但我们在这一领域的进展却很少；学者们仍在试图理解这种两难的医疗状况的解释。相比之下，临床医学实践在向卵巢早衰女性提供保证方面取得了有意义的进步，通过及时干预可以优化她们的生活质量和长期健康。最近，科学家们研究了小 RNA 分子对类固醇生成、细胞凋亡、排卵、性腺和卵巢黄体发育的调节作用。