Calendula suffruticosa Vahl subsp. boissieri Lanza is well-known for its medicinal properties in northeastern Algeria. As far as literature has been able to prove, no study has attempted to make a phytochemical or biological activity evaluation (antioxidants, enzyme inhibitors and antimicrobial potential). This work intends to evaluate, for the first time, the chemical constituents and study the previously mentioned biological activities of C. suffruticosa boissieri essential oil and different sections (flowers, leaves, roots) as well as the effect of changing the solvent (ethanol 70 %) and (methanol 70 %) on these activities. The essential oil of aerial parts of this plant was investigated using GC/MS, and 45 compounds were discovered, accounting for 98.01 % of the essential oil, including 23 monoterpenes, 6 sesquiterpenes, 12 diterpenes, 1 coumarin, 3 alkanes, methyl-cyclohexane (23.73 %), limonene (25.02 %), and o-cymene (13.20 %). Five methods were used to study the antioxidant activity (ABTS, DPPH, CUPRAC, reducing power, and β-carotene bleaching assay), where the results were impressive, especially for the essential oil. In addition, the hydroethanolic solvent (70 %) was found to be the most effective solvent for extraction in general compared to the hydromethanolic solvent (70 %). The extracts and essential oils of C. suffruticosa boissieri also showed a strong inhibiting ability against cholinesterase, tyrosinase, anti-α-amylase, α-glucosidase, and antimicrobials, a very valuable antioxidant, which is a real discovery. Based on these results, it can be said that this plant has important biological activities, so it can be used in the phytotherapy, food, or pharmaceutical sectors.

中文翻译：

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来自阿尔及利亚金盏花 Vahlsubsp. 不同部分的精油和提取物的化学成分和体外抗氧化、抗阿尔茨海默病、抗糖尿病、抗酪氨酸酶和抗菌特性。布瓦谢里兰扎

金盏花_ _ boissieri Lanza 因其在阿尔及利亚东北部的药用价值而闻名。就文献能够证明的而言，还没有研究试图对植物化学或生物活性进行评估（抗氧化剂、酶抑制剂和抗菌潜力）。这项工作旨在首次评估化学成分并研究前面提到的C. suffruticosa boissieri的生物活性精油和不同部分（花、叶、根）以及改变溶剂（乙醇 70%）和（甲醇 70%）对这些活动的影响。采用GC/MS对该植物地上部分的挥发油进行了研究，共发现45种化合物，占挥发油成分的98.01%，其中单萜23种，倍半萜6种，二萜12种，香豆素1种，烷烃3种，甲基环己烷(23.73 %)、柠檬烯 (25.02 %) 和o-聚伞花烃 (13.20 %)。使用五种方法研究抗氧化活性（ABTS、DPPH、CUPRAC、还原力和 β-胡萝卜素漂白测定），结果令人印象深刻，尤其是精油。此外，与氢甲醇溶剂 (70%) 相比，氢乙醇溶剂 (70%) 被发现是通常最有效的萃取溶剂。C. suffruticosa boissieri的提取物和精油也表现出很强的抑制胆碱酯酶、酪氨酸酶、抗α-淀粉酶、α-葡萄糖苷酶和抗菌剂的能力，是一种非常有价值的抗氧化剂，这是一个真正的发现。基于这些结果，可以说这种植物具有重要的生物活性，因此可用于植物疗法、食品或制药领域。