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Multifunctional, breathable MXene-PU mesh electronic skin for wearable intelligent 12-lead ECG monitoring system
Chemical Engineering Journal ( IF 13.3 ) Pub Date : 2022-11-29 , DOI: 10.1016/j.cej.2022.140690
Tianrui Cui , Yancong Qiao , Ding Li , Xiaorui Huang , Le Yang , Anzhi Yan , Zhikang Chen , Jiandong Xu , Xichao Tan , Jinming Jian , Zhen Li , Shourui Ji , Houfang Liu , Yi Yang , Xuegong Zhang , Tian-Ling Ren

With the advent of an aging society and increasing concern for cardiovascular health, comfortable long-term electrocardiographic (ECG) monitoring systems in daily life are much in demand. If the system can give real-time feedback on cardiovascular status and offer timely personalized advice like doctors, it will be beneficial to promote cardiovascular health and alleviate the imbalance of medical resources. Herein, we report a multifunctional, conformal, and air-permeable electronic skin (e-skin) based on MXene-Polyurethane mesh (MPM). When used as ECG electrodes, the e-skin shows ultra-low electrode–skin contact impedance (4.68 kΩ at 1 kHz), high signal-to-noise ratio (16.5 dB), and high breathability (2.1838 kg/m/day), and can be continuously worn for at least 7 days. As a strain sensor, the e-skin exhibits a large measurement range (>40 %) and unique segmental sensitivity (GF = 172.54 in 0 ∼ 18.64 % and 79.38 in 18.64 ∼ 50 %), which is suitable for detecting both subtle and large physiological signals. More significantly, by combining the MPM e-skin with a flexible printed circuit board (FPCB) and a merged convolutional neural network & long-short-term memory (CNN & LSTM) intelligent algorithm, the acquired wearable intelligent e-skin system can realize daily 12-hour 12-lead ECG monitoring with diagnostic accuracy over 99 % for four arrhythmias. These results show that the MPM e-skin has huge potential in multifunctional intelligent healthcare systems. In particular, an intelligent ECG system similar to a “daily doctor” is proposed for daily long-term cardiovascular health monitoring.

中文翻译:


用于可穿戴智能 12 导联心电图监测系统的多功能、透气 MXene-PU 网状电子皮肤



随着老龄化社会的到来以及人们对心血管健康的日益关注,人们对日常生活中舒适的长期心电图(ECG)监测系统的需求很大。如果系统能够像医生一样实时反馈心血管状况并提供及时的个性化建议,将有利于促进心血管健康,缓解医疗资源失衡。在此,我们报告了一种基于 MXene-聚氨酯网格 (MPM) 的多功能、保形且透气的电子皮肤 (e-skin)。当用作心电图电极时,电子皮肤表现出超低电极-皮肤接触阻抗(1 kHz 时为 4.68 kΩ)、高信噪比(16.5 dB)和高透气性(2.1838 kg/m/天) ,可连续佩戴至少7天。作为应变传感器,电子皮肤具有较大的测量范围(>40 %)和独特的分段灵敏度(GF = 172.54 in 0 ∼ 18.64 % and 79.38 in 18.64 ∼ 50 %),适用于检测细微和大的物体生理信号。更重要的是,通过将MPM电子皮肤与柔性印刷电路板(FPCB)以及融合卷积神经网络和长短期记忆(CNN&LSTM)智能算法相结合,所获得的可穿戴智能电子皮肤系统可以实现每日 12 小时 12 导联心电图监测,对四种心律失常的诊断准确率超过 99%。这些结果表明MPM电子皮肤在多功能智能医疗系统中具有巨大的潜力。特别是提出了类似于“日常医生”的智能心电图系统,用于日常长期心血管健康监测。
更新日期:2022-11-29
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