ortho-Quinols are chiral 6-alkyl-6-hydroxycyclohexa-2,4-dienone derivatives of interest to organic chemists because of their natural occurrence, their role as intermediates in the biosynthesis of diverse natural products, and the versatility of their chemical reactivity. Readily accessible from dearomative oxygenation of 2-alkylphenols or other arenols, ortho-quinols constitute useful molecular entities from which structural complexity can be rapidly built, as highlighted herein through many examples of targeted syntheses of natural products, such as trichodimerol.

中文翻译：

---

天然产物（生物）合成中的邻苯二酚

邻苯二酚是有机化学家感兴趣的手性 6-烷基-6-羟基环己-2,4-二烯酮衍生物，因为它们天然存在、在多种天然产物的生物合成中作为中间体的作用以及化学反应的多功能性。邻苯二酚可从 2-烷基酚或其他芳醇的脱芳基氧合反应中轻松获得，构成有用的分子实体，从中可以快速构建结构复杂性，如本文通过许多天然产物（如毛霉二醇）的靶向合成实例所强调的那样。