Implementing the use of alkynyllithium reagents in a stereospecific 1,2-metalate rearrangement-mediated ring opening of polysubstituted cyclopropyl boronic esters provides a variety of tertiary pinacol boranes bearing adjacent tertiary or quaternary carbon stereocenters with high levels of diastereomeric purity. The potential of this strategy was demonstrated through a selection of α- and γ-functionalization of the propargyl boronic esters.

中文翻译：

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炔基锂介导的硼酸化环丙烷的 1,2-金属重排对叔炔丙基硼酸酯的合成与功能化

在多取代环丙基硼酸酯的立体特异性 1,2-金属酸酯重排介导的开环中使用炔基锂试剂提供了各种带有相邻叔或季碳立构中心的叔频哪醇硼烷，具有高水平的非对映体纯度。通过选择炔丙基硼酸酯的 α- 和 γ- 官能化，证明了该策略的潜力。