Defective Interfering Particles with Broad-Acting Antiviral Activity for Dengue, Zika, Yellow Fever, Respiratory Syncytial and SARS-CoV-2 Virus Infection,Microbiology Spectrum

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Defective Interfering Particles with Broad-Acting Antiviral Activity for Dengue, Zika, Yellow Fever, Respiratory Syncytial and SARS-CoV-2 Virus Infection
Microbiology Spectrum ( IF 3.7 ) Pub Date : 2022-11-29 , DOI: 10.1128/spectrum.03949-22
Min-Hsuan Lin ₁ , Dongsheng Li ₁ , Bing Tang ₁ , Li Li ₂ , Andreas Suhrbier _{1,

3} , David Harrich _{1,

3}

Affiliation

DIPs are spontaneously derived virus mutants with deletions in genes that block viral replication. DIPs play important roles in modulation of viral disease, innate immune responses, virus persistence and virus evolution.

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