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Deep dive into a drug pump
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2022-11-28 , DOI: 10.1038/s41589-022-01201-5
Parjit Kaur 1
Affiliation  

Major hurdles remain in understanding the mechanisms of multidrug resistance (MDR) protein efflux. A new study uses deep mutational scanning of a bacterial MDR protein to determine the nature of its drug-binding cavity and understand its function and plasticity.

中文翻译:

深入了解药物泵

在理解多药耐药 (MDR) 蛋白流出的机制方面仍然存在主要障碍。一项新研究使用细菌 MDR 蛋白的深度突变扫描来确定其药物结合腔的性质并了解其功能和可塑性。
更新日期:2022-11-29
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