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Radiation-induced optic neuropathy: a review
British Journal of Ophthalmology ( IF 4.1 ) Pub Date : 2023-06-01 , DOI: 10.1136/bjo-2022-322854
Andrew R Carey 1 , Brandi R Page 2 , Neil Miller 3
Affiliation  

Radiation is a commonly used treatment modality for head and neck as well as CNS tumours, both benign and malignant. As newer oncology treatments such as immunotherapies allow for longer survival, complications from radiation therapy are becoming more common. Radiation-induced optic neuropathy is a feared complication due to rapid onset and potential for severe and bilateral vision loss. Careful monitoring of high-risk patients and early recognition are crucial for initiating treatment to prevent severe vision loss due to a narrow therapeutic window. This review discusses presentation, aetiology, recent advances in diagnosis using innovative MRI techniques and best practice treatment options based on the most recent evidence-based medicine. Data sharing not applicable as no datasets generated and/or analysed for this study.

中文翻译:

辐射引起的视神经病变:综述

放射是头颈部和中枢神经系统肿瘤(良性和恶性)常用的治疗方式。随着免疫疗法等较新的肿瘤学治疗可以延长生存期,放射疗法的并发症也变得越来越普遍。辐射引起的视神经病变是一种可怕的并发症,因为它起病迅速,并可能导致严重和双侧视力丧失。仔细监测高危患者并及早识别对于开始治疗以防止因治疗窗狭窄而导致的严重视力丧失至关重要。本综述讨论了表现、病因学、使用创新 MRI 技术进行诊断的最新进展以及基于最新循证医学的最佳实践治疗方案。数据共享不适用,因为没有为本研究生成和/或分析数据集。
更新日期:2023-05-19
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