Loss of Visceral Fat is Associated with a Reduction in Inflammatory Status in Patients with Metabolic Syndrome,Molecular Nutrition & Food Research

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Loss of Visceral Fat is Associated with a Reduction in Inflammatory Status in Patients with Metabolic Syndrome
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-11-23 , DOI: 10.1002/mnfr.202200264
Sara Castro-Barquero _{1,

2} , Rosa Casas _{1,

2} , Eric B Rimm ₃ , Anna Tresserra-Rimbau _{1,

4} , Dora Romaguera _{1,

5} , J Alfredo Martínez _{1,

6,

7} , Jordi Salas-Salvadó _{1,

8,

9,

10} , Miguel A Martínez-González _{1,

11} , Josep Vidal _{12,

13} , Miguel Ruiz-Canela _{1,

11} , Jadwiga Konieczna _{1,

5} , Emilio Sacanella _{1,

2} , Jesús Francisco García-Gavilán _{1,

8,

9,

10} , Montse Fitó _{1,

14} , Ana García-Arellano _{1,

11,

15} , Ramon Estruch _{1,

2}

Affiliation

Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Institute of Health Carlos III, Madrid, 28029, Spain.
Department of Internal Medicine, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, 08036, Spain.
Departments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Department of Nutrition, Food Science and Gastronomy, XaRTA, INSA, School of Pharmacy and Food Sciences, University of Barcelona, Barcelona, 08028, Spain.
Research Group on Nutritional Epidemiology & Cardiovascular Physiopathology (NUTRECOR), Health Research Institute of the Balearic Islands (IdISBa), Palma de Mallorca, 07120, Spain.
Department of Nutrition, Food Sciences, and Physiology, University of Navarra, Pamplona, 31009, Spain.
Nutritional Genomics and Epigenomics Group, IMDEA Food, CEI UAM + CSIC, Madrid, 28049, Spain.
Departament de Bioquímica i Biotecnologia, Unitat de Nutrició, Universitat Rovira i Virgili, Reus, 43201, Spain.
University Hospital of Sant Joan de Reus, Nutrition Unit, Reus, 43204, Spain.
Institut d'Investigació Sanitària Pere Virgili (IISPV), Reus, 43204, Spain.
Department of Preventive Medicine and Public Health, University of Navarra, IDISNA, Pamplona, 31008, Spain.
CIBER Diabetes y Enfermedades Metabólicas (CIBERDEM), Instituto de Salud Carlos III (ISCIII), Madrid, 28029, Spain.
Department of Endocrinology, Institut d` Investigacions Biomédiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona, Barcelona, 08036, Spain.
Unit of Cardiovascular Risk and Nutrition, Institut Hospital del Mar de Investigaciones Médicas Municipal d`Investigació Médica (IMIM), Barcelona, 08003, Spain.
Emergency Medicine, Osasunbidea, Navarra Regional Health Service, Pamplona, 31003, Spain.

Excessive visceral adipose tissue (VAT) is associated with higher secretion of pro-inflammatory molecules, contributing to systemic inflammation and obesity-related metabolic disturbances.

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