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The Dietary Isothiocyanate Erucin Reduces Kidney Cell Motility by Disturbing Tubulin Polymerization
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-11-22 , DOI: 10.1002/mnfr.202200581
Íris Guerreiro 1, 2 , Bojana Vidovic 3 , João G Costa 1 , Marta Martins 1, 2 , Sandra Ferreira 1, 2 , Nuno G Oliveira 4 , Nuno Saraiva 1 , Ana S Fernandes 1
Affiliation  

Epidemiological evidence associates the consumption of cruciferous vegetables with reduced risk of several cancers, including renal cell carcinoma. Erucin can be generated by in vivo reduction of sulforaphane or by enzymatic hydrolysis of glucoerucin. Contrarily to sulforaphane, only limited studies have addressed the anticancer properties of erucin. This study aims at evaluating the impact of erucin on renal cell biology.

中文翻译:

膳食异硫氰酸酯芥酸通过干扰微管蛋白聚合降低肾细胞运动

流行病学证据表明,食用十字花科蔬菜可降低患多种癌症(包括肾细胞癌)的风险。芥菜素可以通过萝卜硫素的体内还原或葡萄糖芥素的酶水解产生。与萝卜硫素相反,只有有限的研究涉及芥菜素的抗癌特性。本研究旨在评估芥菜素对肾细胞生物学的影响。
更新日期:2022-11-22
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