The Dietary Isothiocyanate Erucin Reduces Kidney Cell Motility by Disturbing Tubulin Polymerization,Molecular Nutrition & Food Research

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The Dietary Isothiocyanate Erucin Reduces Kidney Cell Motility by Disturbing Tubulin Polymerization
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-11-22 , DOI: 10.1002/mnfr.202200581
Íris Guerreiro _{1,

2} , Bojana Vidovic ₃ , João G Costa ₁ , Marta Martins _{1,

2} , Sandra Ferreira _{1,

2} , Nuno G Oliveira ₄ , Nuno Saraiva ₁ , Ana S Fernandes ₁

Affiliation

Epidemiological evidence associates the consumption of cruciferous vegetables with reduced risk of several cancers, including renal cell carcinoma. Erucin can be generated by in vivo reduction of sulforaphane or by enzymatic hydrolysis of glucoerucin. Contrarily to sulforaphane, only limited studies have addressed the anticancer properties of erucin. This study aims at evaluating the impact of erucin on renal cell biology.

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