The past decade has witnessed unprecedented medical progress, which has translated into cardiac surgery being increasingly common and safe. However, complications such as postoperative delirium remain a major concern. Although the pathophysiological changes of delirium after cardiac surgery remain poorly understood, it is widely thought that inflammation and oxidative stress may be potential triggers of delirium. The development of delirium following cardiac surgery is associated with perioperative risk factors. Multiple interventions are being explored to prevent and treat delirium. Therefore, research on the potential role of biomarkers in delirium as well as identification of perioperative risk factors and pharmacological interventions are necessary to mitigate the development of delirium.

中文翻译：

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炎症和氧化应激对心脏手术术后谵妄的影响

过去十年见证了前所未有的医学进步，这已转化为心脏手术越来越普遍和安全。然而，术后谵妄等并发症仍然是一个主要问题。尽管心脏手术后谵妄的病理生理变化仍知之甚少，但人们普遍认为炎症和氧化应激可能是谵妄的潜在诱因。心脏手术后发生谵妄与围手术期危险因素有关。正在探索多种干预措施来预防和治疗谵妄。因此，研究生物标志物在谵妄中的潜在作用以及确定围手术期危险因素和药物干预对于减轻谵妄的发展是必要的。