Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice,Molecular Nutrition & Food Research

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Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-11-19 , DOI: 10.1002/mnfr.202200317
Fuqiang Zhao ₁ , Tingting Ma ₁ , Xin Zhang ₁ , Qiancheng Zhao ₂ , Kexue Zhu ₃ , Jun Cao ₁ , Zhongyuan Liu _{1,

4} , Xuanri Shen _{1,

4} , Chuan Li _{1,

4}

Affiliation

Immunosuppression is one of the major risk factors for a series of diseases, such as tumor, rheumatoid arthritis, and microbial infection. Various natural products have attracted wide attention due to their immunomodulatory activities. Herein, the study investigates the regulation of Holothuria leucospilota polysaccharides (HLP) in immunosuppressed mice.

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