In order to tackle the issue of terramycin mycelial dreg (TMD) diagnosis and removal of terramycin and antibiotic resistance genes (ARGs), this study adopted aerobic composting (AC) technology and added homemade compound microbial inoculum (HCMI) to promote the AC of TMD and enhance the removal of terramycin and ARGs. The findings demonstrated that terramycin residue could be basically harmless after AC. Moreover, HCMI not only reduced QacB and tetH but also increased the degradation rates of VanRA, VanT, and dfrA24 by 40.81%, 5.65%, and 54.18%, respectively. The HCMI improved the removal rate of ARG subtypes to a certain extent. According to redundancy analysis, during AC, the succession of the microbial community had a stronger influence on the variance of ARG subtype than the environmental conditions. Differences in the abundance of various bacteria due to changes in temperature may be an intrinsic mechanism for the variation of ARG subtypes.

为了解决土霉素菌丝体残渣（TMD）诊断和去除土霉素和抗生素抗性基因（ARGs）的问题，本研究采用好氧堆肥（AC）技术，添加自制复合微生物菌剂（HCMI）促进TMD的AC并增强土霉素和ARGs的去除。结果表明AC后土霉素残留基本无害。此外，HCMI 不仅降低了 Qac B 和tet H，还提高了Van RA、Van T 和dfr的降解率A24 分别增长 40.81%、5.65% 和 54.18%。HCMI在一定程度上提高了ARG亚型的去除率。根据冗余分析，在AC期间，微生物群落的演替对ARG亚型方差的影响大于环境条件。由于温度变化导致的各种细菌的丰度差异可能是 ARG 亚型变异的内在机制。