The use of Additive Manufacturing for the fabrication of chemical reactors for flow chemistry is a promising field as it can lead to several improvements over more standard equipment. In this work, two different reactors were fabricated and compared: a Honeycomb monolith reactor with straight channels and a Periodic Open Cell Structure reactor. The Honeycomb monolith reactor was used as an example of a standard reactor (not necessarily additive manufactured) while the Periodic Open Cell Structure is a promising new type of reactor, which improves some key features, such as contact surface area and porosity. The two reactors were manufactured by Stereolithography technology with a high temperature resin and their internal surfaces were chemically activated by the grafting of palladium. For the surface activation, a two-step procedure was developed, firstly using NaOH and in a second step an aqueous solution of Na₂PdCl₄. After activation, a heterogeneous catalytic reaction was used to characterize the performance of the two fabricated reactors. The chosen reaction was the Suzuki–Miyaura reaction, which is commonly used in the pharmaceutical industry. The experimental results showed that, for equal contact surface area, the new designed reactor had better performance compared to the standard geometry.

中文翻译：

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增材制造用于有机金属催化反应的微结构反应器

使用增材制造来制造流动化学的化学反应器是一个很有前途的领域，因为它可以导致对更多标准设备的多项改进。在这项工作中，制造并比较了两种不同的反应器：具有直通道的蜂窝整体式反应器和周期性开孔结构反应器。蜂窝整体式反应器用作标准反应器（不一定是增材制造）的示例，而周期性开孔结构是一种很有前途的新型反应器，它改进了一些关键特性，例如接触表面积和孔隙率。这两个反应器采用高温树脂立体光刻技术制造，其内表面通过接枝钯进行化学活化。对于表面活化，开发了一个两步程序，₂氯化钯₄。活化后，使用多相催化反应来表征两个制造的反应器的性能。选择的反应是制药工业中常用的铃木-宫浦反应。实验结果表明，对于相同的接触表面积，新设计的反应器与标准几何形状相比具有更好的性能。