Intestinal mucin glycosylation is important for mucus-bacterial homeostasis and is altered in disease. In this issue of The EMBO Journal, Ilani et al (2022) identify the Golgi enzyme quiescin sulfhydryl oxidase 1 (QSOX1) as a novel mucus regulator by controlling mucin sialylation.

中文翻译：

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高尔基体氧传感器控制肠道粘蛋白糖基化

肠道粘蛋白糖基化对于粘液细菌稳态很重要，并且在疾病中发生改变。在本期《EMBO 杂志》中，Ilani等人(2022) 通过控制粘蛋白唾液酸化，将高尔基体静默蛋白巯基氧化酶 1 (QSOX1) 确定为一种新型粘液调节剂。