All-solid-state potentiometric sensors that are easily miniaturized and arrayed are widely used in home diagnostics. However, changes in sample matrix compositions tend to affect the basic potential of the potentiometric sensor, and pH of sample could change the response slope, thus affecting the detection reliability. This study takes the detection of glucose in urine as a model to increase the reliability of potentiometric sensors in home detection. PtAu/CNTs nanozyme modified by diboronic acid has been designed, showing better catalytic selectivity for glucose by experiments and theoretical calculations. Moreover, glucose electrode group in a multi-calibration glucose potentiometric sensing array can realize the basic potential calibration of sensing channel by the calibration channel. Meanwhile, the pH electrode group can not only measure the urine pH, but also calibrate the response slope of the glucose electrode group, thus improving the reliability of home detection.

易于小型化和阵列化的全固态电位传感器广泛用于家庭诊断。然而，样品基质组成的变化往往会影响电位传感器的基本电位，样品的pH值会改变响应斜率，从而影响检测可靠性。本研究以检测尿液中的葡萄糖为模型，以提高电位传感器在家庭检测中的可靠性。设计了二硼酸修饰的 PtAu/CNTs 纳米酶，通过实验和理论计算显示出对葡萄糖具有更好的催化选择性。并且，多标定葡萄糖电位传感阵列中的葡萄糖电极组可以通过标定通道实现传感通道的基本电位标定。同时，