Mediterranean Diet, Energy Restriction, Physical Activity, and Atherogenicity of Very-Low Density Lipoproteins: Findings from Two Randomized Controlled Trials,Molecular Nutrition & Food Research

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Mediterranean Diet, Energy Restriction, Physical Activity, and Atherogenicity of Very-Low Density Lipoproteins: Findings from Two Randomized Controlled Trials
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-11-10 , DOI: 10.1002/mnfr.202200338
Karla Alejandra Pérez-Vega _{1,

2,

3} , Olga Castañer _{1,

2} , Albert Sanllorente _{1,

2} , Camille Lassale _{1,

2} , Emilio Ros _{2,

4,

5} , Xavier Pintó _{2,

6} , Ramón Estruch _{2,

5,

7} , Jordi Salas-Salvadó _{2,

8,

9} , Dolores Corella _{2,

10} , Ángel M Alonso-Gómez _{2,

11} , Lluis Serra-Majem _{2,

12,

13} , Cristina Razquin _{2,

14} , Miquel Fiol _{2,

15} , José Lapetra _{2,

16} , Enrique Gómez-Gracia _{2,

17} , Francisco J Tinahones _{2,

18} , Álvaro Hernáez _{2,

19,

20} , Montserrat Fitó _{1,

2}

Affiliation

Hospital del Mar Medical Research Institute (IMIM), Barcelona, 08003, Spain.
Consorcio Centro de Investigación Biomédica En Red (CIBER), M.P. Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, 28029, Spain.
PhD Program in Food Science and Nutrition, Faculty of Pharmacy and Food Science, Universitat de Barcelona, Barcelona, 08028, Spain.
Lipid Clinic, Endocrinology and Nutrition Service, Hospital Clínic, Barcelona, 08036, Spain.
August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, 08036, Spain.
Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, 08907, Spain.
Internal Medicine Service, Hospital Clinic, Barcelona, 08036, Spain.
Universitat Rovira i Virgili, Universitat Rovira i Virgili, Departament de Bioquimica i Biotecnologia, Unitat de Nutrició Humana, Reus, 43201, Spain.
Institut d'Investigació Pere Virgili, Hospital Universitari Sant Joan de Reus, Reus, 43204, Spain.
Department of Preventive Medicine, Universidad de Valencia, Valencia, 46010, Spain.
Bioaraba Health Research Institute, Osakidetza Basque Health Service, Araba University Hospital, University of the Basque Country UPV/EHU, Vitoria-Gasteiz, 01009, Spain.
Instituto de Investigaciones Biomédicas y Sanitarias, Universidad de Las Palmas de Gran Canaria, Las Palmas, 35016, Spain.
Centro Hospitalario Universitario Insular Materno Infantil, Servicio Canario de Salud, Las Palmas, 35016, Spain.
Department of Preventive Medicine and Public Health, IdiSNA, University of Navarra, Pamplona, 31008, Spain.
Health Research Institute of the Balearic Islands (IdISBa), Hospital Son Espases, Palma de Mallorca, 07120, Spain.
Department of Family Medicine-Research Unit, Distrito Sanitario Atención Primaria Sevilla, Sevilla, 41013, Spain.
Department of Preventive Medicine and Public Health, Universidad de Málaga, Málaga, 29071, Spain.
Department of Endocrinology, Biomedical Research Institute of Málaga, Virgen de la Victoria Hospital, University of Málaga, Málaga, 29006, Spain.
Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, 0463, Norway.
Blanquerna School of Health Sciences, Universitat Ramon Llull, Barcelona, 08025, Spain.

Some very-low density lipoprotein (VLDL) properties may render them more pro-atherogenic. We aimed to assess whether a Mediterranean diet (MedDiet) or an energy-reduced MedDiet with increased physical activity improves them.

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