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Broad-capture proteomics and machine learning for early detection of type 2 diabetes risk
Nature Medicine ( IF 58.7 ) Pub Date : 2022-11-10 , DOI: 10.1038/s41591-022-02056-y


Impaired glucose tolerance (IGT) is a common condition that affects glucose control after sugar consumption. Isolated IGT is undetected by screening and diagnostic strategies, leaving affected individuals at high risk of developing diabetes. Here, a machine-learning framework identifies a three-protein signature for detecting isolated IGT from a single blood sample.

中文翻译:

用于早期检测 2 型糖尿病风险的广泛捕获蛋白质组学和机器学习

糖耐量受损 (IGT) 是影响糖摄入后血糖控制的常见病症。孤立的 IGT 无法通过筛查和诊断策略检测到,使受影响的个体处于患糖尿病的高风险中。在这里,机器学习框架识别出一种三蛋白特征,用于从单个血液样本中检测孤立的 IGT。
更新日期:2022-11-10
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