Two new lignans (1–2) and a new octaketide (12), together with twenty-nine known compounds (3–11, 13–32) were isolated and identified from the aerial part of Pogostemon cablin. Their chemical structures were revealed mainly through NMR and MS data. The absolute configuration of 1 and 2 was deduced by comparing its experimental CD with the calculated ECD spectra. The inhibitory activities of the isolated compounds on LPS-stimulated nitric oxide (NO) production in RAW 264.7 cells were investigated. At a concentration of 25 μM, compounds 1 and 11 showed approximately equal NO inhibitory effects to that of aminoguanidine.

中文翻译：

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广藿香地上部分的木酚素和苯乙醇苷

从广藿香的地上部分分离并鉴定了两种新的木酚素 ( 1 – 2 ) 和一种新的八酮内酯 ( 12 ) 以及二十九种已知化合物 ( 3 – 11、13 – 32 ) 。它们的化学结构主要通过 NMR 和 MS 数据揭示。通过将其实验 CD 与计算的 ECD 光谱进行比较，推导出1和2的绝对构型。研究了分离化合物对 RAW 264.7 细胞中 LPS 刺激的一氧化氮 (NO) 产生的抑制活性。在浓度为 25 μM 时，化合物1和11显示出与氨基胍大致相等的 NO 抑制作用。