The virtual lens model has important value in ophthalmic research, clinical diagnosis, and treatment. However, the establishment of personalized lens models and the verification of accommodation accuracy have not been paid much attention. We proposed a personalized lens model establishment and the accommodation accuracy evaluation method based on sweep-source optical coherence tomography (SS-OCT). Firstly, SS-OCT is used to obtain a single lens image in the maximum accommodation state. After refraction correction, boundary detection, and curve fitting, the central curvature radius, thickness, and lens nucleus contour of the anterior and posterior surfaces of the lens were obtained. Secondly, a personalized finite element model improved from Burd’s model was established using these individual parameters, and the adaptation process of the lens model was simulated by pulling the suspensory ligament. Finally, the shape and refractive power changes of the real human lens under different accommodation stimuli were collected and compared with the accommodation process of the finite element model. The results show that the accommodation process of the finite element model is highly consistent with that of the real lens. From the un-accommodation state to the maximum-accommodation state, the difference rate of all geometric and refractive parameters between the two is less than 5%. Thus, the personalized lens finite element model obtained by the calibration and correction of the existing model can accurately simulate the regulation process of a specific human lens. This work helps to provide a valuable theoretical basis and research ideas for the study of clinical diagnosis and treatment of related diseases.

中文翻译：

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基于扫描源光学相干断层扫描的晶体透镜个性化有限元模型的建立

虚拟晶状体模型在眼科研究、临床诊断和治疗中具有重要价值。但是，个性化镜片模型的建立和调节精度的验证一直没有受到重视。我们提出了一种基于扫描源光学相干断层扫描（SS-OCT）的个性化镜片模型建立和调节精度评估方法。首先，SS-OCT用于获取最大适应状态下的单镜头图像。经过屈光校正、边界检测和曲线拟合，得到晶状体前后表面的中心曲率半径、厚度和晶状体核轮廓。其次，使用这些单独的参数建立了从 Burd 模型改进的个性化有限元模型，并通过牵拉悬韧带模拟晶状体模型的适应过程。最后，收集真实人体晶状体在不同调节刺激下的形状和屈光力变化，并与有限元模型的调节过程进行比较。结果表明，有限元模型的适应过程与真实镜头的适应过程高度一致。从非调节状态到最大调节状态，两者所有几何参数和折射参数的差异率小于5%。因此，通过对现有模型的标定和校正得到的个性化镜片有限元模型可以准确地模拟特定人体镜片的调节过程。