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Activation of Calcium-Sensing Receptor in the Area Postrema Inhibits Food Intake via Glutamatergic and GABAergic Signaling Pathways
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-10-25 , DOI: 10.1002/mnfr.202200245
Jinfang Huang 1 , Qian Xu 1 , Yuhang Li 1 , Xiaoman He 1 , Yajie Guo 1 , Xiangrong Sun 1
Affiliation  

A high-protein diet has become a popular way to lose weight. Calcium-sensing receptor (CaSR) is activated by amino acids in addition to calcium ions. CaSR shows dense expression in the area postrema (AP), which participates in feeding regulation. The effect of CaSR in the AP on food intake and the potential mechanism involved is investigated.

中文翻译:

极后区钙敏感受体的激活通过谷氨酸能和 GABA 能信号通路抑制食物摄入

高蛋白饮食已经成为一种流行的减肥方式。除钙离子外,钙敏感受体 (CaSR) 还被氨基酸激活。CaSR 在参与摄食调节的极后区 (AP) 中表现出密集表达。研究了 AP 中 CaSR 对食物摄入的影响以及所涉及的潜在机制。
更新日期:2022-10-25
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