Acoustic patterning of micro-particles has many important biomedical applications. However, fabrication of such microdevices is costly and labor-intensive. Among conventional fabrication methods, photo-lithography provides high resolution but is expensive and time consuming, and not ideal for rapid prototyping and testing for academic applications. In this work, we demonstrate a highly efficient method for rapid prototyping of acoustic patterning devices using laser manufacturing. With this method we can fabricate a newly designed functional acoustic device in 4 hours. The acoustic devices fabricated using this method can achieve sub-wavelength, complex and non-periodic patterning of microparticles and biological objects with a spatial resolution of 60 μm across a large active manipulation area of 10 × 10 mm².

中文翻译：

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使用激光制造的功能声学设备的快速原型制作

微粒的声学图案具有许多重要的生物医学应用。然而，此类微型设备的制造成本高昂且劳动强度大。在传统的制造方法中，光刻可提供高分辨率，但价格昂贵且耗时，并不适合用于学术应用的快速原型制作和测试。在这项工作中，我们展示了一种使用激光制造快速制作声学图案形成装置原型的高效方法。使用这种方法，我们可以在 4 小时内制造出新设计的功能性声学设备。^{使用这种方法制造的声学设备可以在 10 × 10 mm 2}的大活动操作区域上以 60 μm 的空间分辨率实现微粒和生物物体的亚波长、复杂和非周期性图案化。