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The electrodynamics of rod-like microparticles based on optically induced dielectrophoresis
Electrophoresis ( IF 3.0 ) Pub Date : 2022-10-09 , DOI: 10.1002/elps.202200102
Liuyong Shi 1 , Xiangtao Zhong 1 , Tao Wu 1 , Qin Bian 1 , Xiaomei Liu 1 , Huaqing Miao 2 , Yongbo Deng 3 , Binfeng Yin 4 , Teng Zhou 1
Affiliation  

Due to its characteristics of noncontact, non-damage, high flux, and easy-to-achieve flexible manipulation, optically induced dielectrophoresis (ODEP) technology has been employed to manipulate microspherical biological particles, including separation, enrichment, capture, arrangement, and fusion. However, in nature, biomolecules are morphologically diverse, and some of them are rodlike. In order to illustrate the electrodynamics of rodlike particles under the action of ODEP, a transient multi-physical field coupling model of ODEP chip under the hypothesis of electrical double layer thin layer was established in this paper. The arbitrary Lagrangian–Eulerian method is used to track single-rod particle in the strong coupled flow field and electric field simultaneously. The influence of several key factors, including the applied alternating current (AC) electric voltage, the width of optical bright area, and the initial position of particle, on the trajectory of particle center was analyzed in positive dielectrophoresis (DEP) action and negative DEP action, respectively. Especially, the planar motion process of rodlike particles was discussed together. The research results reveal the electrodynamics behavior of rodlike particles based on the action of ODEP, which may provide theoretical support for the further design of rodlike biological cells manipulation chip based on AC ODEP technology in the future.

中文翻译:

基于光诱导介电泳的棒状微粒的电动力学

光诱导介电泳(ODEP)技术由于其非接触、无损伤、高通量和易于实现灵活操作等特点,被用于对微球生物颗粒进行分离、富集、捕获、排列和融合等操作。 . 然而,在自然界中,生物分子在形态上是多种多样的,其中一些是棒状的。为了说明棒状粒子在ODEP作用下的电动力学,本文建立了双电层薄层假设下的ODEP芯片瞬态多物理场耦合模型。任意拉格朗日-欧拉方法用于在强耦合流场和电场中同时跟踪单棒粒子。几个关键因素的影响,分别在正介电泳(DEP)作用和负介电泳作用下分析了施加的交流(AC)电压,光学亮区宽度和粒子在粒子中心轨迹上的初始位置。特别地,一起讨论了棒状粒子的平面运动过程。研究结果揭示了棒状粒子基于ODEP作用的电动力学行为,可为今后进一步设计基于AC ODEP技术的棒状生物细胞操控芯片提供理论支持。一起讨论了棒状粒子的平面运动过程。研究结果揭示了棒状粒子基于ODEP作用的电动力学行为,可为今后进一步设计基于AC ODEP技术的棒状生物细胞操控芯片提供理论支持。一起讨论了棒状粒子的平面运动过程。研究结果揭示了棒状粒子基于ODEP作用的电动力学行为,可为今后进一步设计基于AC ODEP技术的棒状生物细胞操控芯片提供理论支持。
更新日期:2022-10-09
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