The US needs to plan for what happens if the inactivated polio vaccine and hygiene measures do not stop polio transmission, say Nina Schwalbe and Jay Varma On 13 September 2022, the United States was added to a list compiled by the World Health Organization (WHO) of countries with circulating poliovirus, and joined a group that includes Somalia, Democratic Republic of Congo, and Yemen.1 In late July, the New York State Department of Health reported that a person had been paralysed as a result of a polio infection likely acquired in the US.23 This was the first case of domestically acquired infection in the US since 2005.34 Subsequently, the same variant of poliovirus was detected in sewage samples in several counties in New York, indicating that hundreds of thousands of people may have recently been infected.5 In early September, New York State’s governor declared a disaster in the state. The stakes are high to get the public health response right. Although most poliovirus infections cause no or mild symptoms, the virus can cause meningitis (one to five cases in 100), irreversible paralysis (ranging from one in 200 to one in 2000 people infected depending on the virus type), and even death (between approximately two to 10 people in 100 paralysis cases).23456 If the US wants to gain control of transmission and prepare for the worst, it needs to revise its polio vaccine …

中文翻译：

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美国需要准备引进新型口服脊髓灰质炎疫苗

纽约州州长宣布该州发生灾难。要做出正确的公共卫生反应，风险很高。尽管大多数脊髓灰质炎病毒感染不会引起症状或症状轻微，但该病毒可引起脑膜炎（每 100 人中有 1 至 5 例）、不可逆性麻痹（根据病毒类型，感染人数从 200 分之一到 2000 分之一不等），甚至死亡（介于在 100 例瘫痪病例中大约有 2 到 10 人）。23456 如果美国想要控制传播并为最坏的情况做准备，它需要修改其脊髓灰质炎疫苗……