Frontiers in Oncology ( IF 3.5 ) Pub Date : 2022-09-30 , DOI: 10.3389/fonc.2022.997492 Razan Mansour 1 , Justin Z Amarin 1 , Abdallah Al-Ani 1 , Maysa Al-Hussaini 2 , Asem Mansour 3
The Palestinian Ministry of Health (MoH) routinely refers Palestinian patients with cancer to King Hussein Cancer Center (KHCC), the largest cancer center in the Middle East.
We aimed to describe the characteristics of Palestinian patients with cancer.
We performed a retrospective chart review of all Palestinian patients with cancer who were treated at KHCC during 2018 and 2019, of which demographic and clinical characteristics were presented.
We initially started with 521 cases, out of which 41 (7.9%) cases were excluded due to misdiagnosis as malignant on pathology review. We included 480 patients with a confirmed diagnosed of cancer. Most patients were adults (88.8%) with a mean age of 50.0 ± 15.0 years ranging from 19 to 87 years. The most common cancer sites in adult men, who comprised 46.9% of the cohort were the hematolymphoid system (23.5%), followed by the digestive system (17.5%), and lung and pleura (11.5%). In women (53.1%), the most common cancer sites were the breast (46.0%), followed by the digestive system (15.0%), and the hematolymphoid system (10.2%). Children and adolescents accounted for 11.3% of the total cases, among which the hematolymphoid system was the most common cancer site (50%), followed by the brain (14.8%). About 36.0% of all patients presented with advanced-stage disease (i.e., distant metastasis).
The most common cancer sites in our cohort are generally similar to data from the Palestinian territories. Many patients presented with advanced-stage disease, which signals the need for awareness campaigns and screening programs. Benign tumors are misdiagnosed in many patients as cancer. The limited resources and facilities including human resources remain important challenges to the proper and timely diagnosis and management of cancer among Palestinians living in the Palestinian Territories.
中文翻译:
侯赛因国王癌症中心的巴勒斯坦癌症患者
巴勒斯坦卫生部 (MoH) 经常将患有癌症的巴勒斯坦患者转诊至中东最大的癌症中心侯赛因国王癌症中心 (KHCC)。
我们旨在描述巴勒斯坦癌症患者的特征。
我们对 2018 年和 2019 年期间在 KHCC 接受治疗的所有巴勒斯坦癌症患者进行了回顾性图表审查,其中介绍了人口统计学和临床特征。
我们最初从 521 例病例开始,其中 41 例 (7.9%) 病例因病理检查误诊为恶性而被排除。我们纳入了 480 名确诊为癌症的患者。大多数患者是成年人(88.8%),平均年龄为 50.0 ± 15.0 岁,介于 19 至 87 岁之间。成年男性中最常见的癌症部位是血液淋巴系统(23.5%),其次是消化系统(17.5%)和肺和胸膜(11.5%),占该队列的 46.9%。在女性(53.1%)中,最常见的癌症部位是乳房(46.0%),其次是消化系统(15.0%)和淋巴系统(10.2%)。儿童和青少年占总病例的11.3%,其中血液淋巴系统是最常见的癌症部位(50%),其次是脑部(14.8%)。大约36。
我们队列中最常见的癌症部位通常与来自巴勒斯坦领土的数据相似。许多患者出现晚期疾病,这表明需要开展宣传活动和筛查计划。许多患者将良性肿瘤误诊为癌症。包括人力资源在内的有限资源和设施仍然是生活在巴勒斯坦领土上的巴勒斯坦人对癌症进行适当和及时诊断和管理的重要挑战。