Objective. To study the effect of Mirena intrauterine device (IUD) on endometrial thickness, life quality score, and curative effect in patients with perimenopausal abnormal uterine bleeding. Methods. Eighty patients with perimenopausal abnormal uterine bleeding cured from January 2020 to December 2021 were enrolled as the object of study. According to random number table, the patients were classified into the study () and control () groups. The control cases were cured with medroxyprogesterone. The study cases were cured with Mirena IUD. The effective rate of clinical therapies was evaluated after 3 months of treatment. The endometrial thickness, menstrual volume score, and life quality score (WHOQOL-BREF) was measured after 1 month, 2 months, and 3 months of treatment. Results. The effective rate of patients with Mirena IUD for 3 months was higher compared to the control group (). The endometrial thickness and menstrual volume scores of study cohort after 1 month, 2 months, and 3 months following treatment were remarkably lower than those before treatment () and were considerably lower than those of control cohort (). The hemoglobin level of the studied cases after 1 month, 2 months, and 3 months after therapy was remarkably upregulated () and was greatly higher compared to the controlled cases (). After 3-month treatment, the WHOQOL-BREF score of the study group was higher compared to the control group (). Conclusion. The Mirena IUD is far more effective in the treatment of perimenopausal abnormal uterine bleeding and is helpful in reducing the thickness of the endometrium. Patients’ menstrual flow can be controlled, and anemia can be corrected; thus, patients improve their quality of life and health status and can be considered for further promotion.

中文翻译：

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Mirena宫内节育器对围绝经期异常子宫出血患者子宫内膜厚度、生活质量评分及疗效的影响

客观。研究 Mirena 宫内节育器 (IUD) 对围绝经期异常子宫出血患者子宫内膜厚度、生活质量评分及疗效的影响。方法。纳入2020年1月至2021年12月治愈的围绝经期异常子宫出血患者80例作为研究对象。根据随机数字表，将患者分为研究对象（)和控制 ()组。对照组用甲羟孕酮治愈。研究病例使用 Mirena IUD 治愈。治疗3个月后评价临床治疗的有效率。分别在治疗1个月、2个月、3个月后测量子宫内膜厚度、月经量评分和生活质量评分（WHOQOL-BREF）。结果。Mirena IUD 患者 3 个月的有效率高于对照组（）。治疗后 1 个月、2 个月和 3 个月研究队列的子宫内膜厚度和月经量评分均显着低于治疗前。）并且大大低于对照组（）。研究病例治疗1个月、2个月、3个月后血红蛋白水平显着上调。）并且与对照病例（）。治疗3个月后，研究组WHOQOL-BREF评分高于对照组（）。 结论。Mirena IUD 在治疗围绝经期异常子宫出血方面要有效得多，并且有助于减少子宫内膜的厚度。可以控制患者的月经量，纠正贫血；因此，患者提高了他们的生活质量和健康状况，可以考虑进一步推广。