Objective 

The aim of the study is to quantify the effects of virtual reality–based exercise on balance after stroke.

Design 

The PubMed, Embase, Cochrane Library, Cumulative Index of Nursing and Allied Health Literature, and Web of Science databases were searched until December 31, 2021. Independent investigators abstracted data, assessed the quality of the evidence, and rated the certainty of the evidence. The intergroup differences were determined by calculating mean difference and 95% confidence interval by RevMan 5.3 software.

Results 

Fourteen randomized controlled trials involving 423 stroke patients were included. Patients who received virtual reality–based exercise illustrated marked improvements in the Berg Balance Scale (mean difference, 1.35; 95% confidence interval, 0.58 to 1.86; P < 0.00001; I² = 44%), Timed Up and Go test (mean difference, −0.81; 95% confidence interval, −1.18 to −0.44; P < 0.0001; I² = 0%), Functional Reach Test (mean difference, 3.06; 95% confidence interval, 1.31–4.80; P = 0.0006; I² = 0%), 10-Meters Walking Test (mean difference, −1.53; 95% confidence interval, −2.92 to −0.13; P = 0.03; I² = 33%), and Modified Barthel Index (mean difference, 5.26; 95% confidence interval, 1.70 to 8.82; P = 0.004; I² = 0%) compared with the control group.

Conclusions 

Existing low-evidence analyses showed that virtual reality–based exercise could effectively and safely improve balance in chronic stroke. Longer-term virtual reality–based exercise was more effective on functional ability of stroke.

中文翻译：

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基于虚拟现实的运动对中风患者平衡的影响：系统评价和荟萃分析

客观的 

该研究的目的是量化基于虚拟现实的锻炼对中风后平衡的影响。

设计 

PubMed、Embase、Cochrane 图书馆、护理和联合健康文献累积索引以及 Web of Science 数据库的检索截止日期为 2021 年 12 月 31 日。独立调查人员提取数据、评估证据质量并对证据的确定性进行评级。通过RevMan 5.3软件计算平均差和95%置信区间来确定组间差异。

结果 

纳入了 14 项随机对照试验，涉及 423 名中风患者。接受基于虚拟现实的锻炼的患者在 Berg 平衡量表（平均差异，1.35；95% 置信区间，0.58 至 1.86；P < 0.00001；I 2 = 44 ^%）、Timed Up and Go 测试（平均差异，−0.81；95% 置信区间，−1.18 至 −0.44；P < 0.0001；I ² = 0%），功能范围测试（平均差，3.06；95% 置信区间，1.31–4.80；P = 0.0006；I ² = 0%）、10 米步行测试（平均差，-1.53​​；95% 置信区间，-2.92 至 -0.13；P = 0.03；I ² = 33%）和修正巴塞尔指数（平均差，5.26；95）与对照组相比，%置信区间，1.70至8.82；P = 0.004；I ^{2 = 0%）。}

结论 

现有的低证据分析表明，基于虚拟现实的锻炼可以有效、安全地改善慢性中风的平衡能力。长期基于虚拟现实的锻炼对中风的功能能力更有效。