Açaí (Euterpe oleracea Mart.) juice is rich in phenolic compounds with high antioxidant capacity. It has been observed that the use of antioxidants may be an additional strategy to nonsurgical periodontal therapy as well as to prevent alveolar bone loss. Thus, the objective of this study was to investigate the effects of açaí supplementation on experimental periodontitis in rats. Twenty male Rattus norvegicus (Wistar) rats were assigned into control, açaí, experimental periodontitis, and experimental periodontitis with açaí supplementation groups. Periodontitis was induced by placing ligatures around the lower first molars. Animals in the açaí groups received 0.01 mL/g of clarified açaí juice for 14 days by intragastric gavage. At the end of the experimental period, blood was collected to assess the reduced glutathione (GSH), Trolox equivalent antioxidant capacity (TEAC), and lipid peroxidation (TBARS) levels. Moreover, hemimandibles were analyzed by micro-computed tomography (micro-CT) for alveolar bone loss and bone quality. Açaí supplementation increased blood total antioxidant capacity and decreased lipid peroxidation. It also reduced alveolar bone loss when compared to the experimental periodontitis group. Moreover, clarified açaí per se modulated the oxidative biochemistry and bone microstructure. Thus, açaí may be considered a viable alternative for managing periodontal oxidative stress and preventing alveolar bone loss.

中文翻译：

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Açaí (Euterpe oleracea Mart.) 减轻大鼠实验性牙周炎的氧化应激和牙槽骨损伤

Açaí ( Euterpe oleracea Mart.) 果汁富含具有高抗氧化能力的酚类化合物。据观察，使用抗氧化剂可能是非手术牙周治疗以及预防牙槽骨丢失的额外策略。因此，本研究的目的是研究巴西莓补充剂对大鼠实验性牙周炎的影响。二十只雄性褐家鼠(Wistar) 大鼠被分配到对照组、阿萨伊、实验性牙周炎和实验性牙周炎与阿萨伊补充组。通过在较低的第一磨牙周围放置结扎线来诱发牙周炎。阿萨伊组的动物通过灌胃接受 0.01 mL/g 澄清阿萨伊汁 14 天。在实验期结束时，收集血液以评估还原型谷胱甘肽 (GSH)、Trolox 等效抗氧化能力 (TEAC) 和脂质过氧化 (TBARS) 水平。此外，通过微型计算机断层扫描 (micro-CT) 分析下颌骨的牙槽骨丢失和骨质量。巴西莓补充剂可增加血液总抗氧化能力并减少脂质过氧化。与实验性牙周炎组相比，它还减少了牙槽骨丢失。而且，澄清的巴西莓本身调节了氧化生化和骨骼微结构。因此，阿萨伊可能被认为是管理牙周氧化应激和预防牙槽骨丢失的可行替代品。