Enhancing the oral and topical insecticidal efficacy of a commercialized spider venom peptide biopesticide via fusion to the carrier snowdrop lectin (Galanthus nivalis agglutinin),Pest Management Science

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Enhancing the oral and topical insecticidal efficacy of a commercialized spider venom peptide biopesticide via fusion to the carrier snowdrop lectin (Galanthus nivalis agglutinin)
Pest Management Science ( IF 3.8 ) Pub Date : 2022-09-26 , DOI: 10.1002/ps.7198
Nur Afiqah Sukiran ₁ , Prashant Pyati _{1,

2} , Caitlin E Willis _{1,

3} , Adrian P Brown ₁ , Jennifer J Readshaw ₁ , Elaine C Fitches ₁

Affiliation

Spear®-T sold as a contact foliar spray for the control of glasshouse pests such as aphids, thrips, spider mites and whiteflies, contains the recombinant spider venom peptide GS-ω/κ-HxTx-Hv1h (named as GS-ω/κ-HxTx-Hv1a by Vestaron) as the active ingredient. Here we investigate whether fusion of the peptide to snowdrop lectin, (Galanthus nivalis agglutinin; GNA) enhances the efficacy of this venom peptide towards aphid pests.

中文翻译：

通过与载体雪花莲凝集素（雪花莲凝集素）的融合提高商业化蜘蛛毒肽生物农药的口服和局部杀虫功效

Spear®-T 作为接触式叶面喷雾剂出售，用于控制温室害虫，如蚜虫、蓟马、红蜘蛛和粉虱，含有重组蜘蛛毒肽 GS-ω/κ-HxTx-Hv1h（命名为 GS-ω/κ -Vestaron 的 HxTx-Hv1a）作为活性成分。在这里，我们研究肽与雪花莲凝集素（Galanthus nivalis凝集素；GNA）的融合是否增强了这种毒液肽对蚜虫害虫的功效。

更新日期：2022-09-26

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