Sarcopenia is defined as an age-related progressive loss of muscle mass and/or strength. Although different factors can contribute to this disease, the underlying mechanisms remain unclear. We assessed transcriptional heterogeneity in skeletal muscles from sarcopenic and control mice at single-cell resolution.

中文翻译：

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单细胞 RNA 测序揭示干扰素诱导的鸟苷酸结合蛋白与肌肉减少症有关


肌肉减少症被定义为与年龄相关的肌肉质量和/或力量的进行性丧失。尽管不同的因素可能导致这种疾病，但潜在的机制仍不清楚。我们以单细胞分辨率评估了少肌症小鼠和对照小鼠骨骼肌的转录异质性。