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Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome
Pediatric Dermatology ( IF 1.2 ) Pub Date : 2022-09-24 , DOI: 10.1111/pde.15116
Adrià Plana-Pla 1, 2 , Laura Condal 1, 2 , Ane Jaka 1, 2 , Ignacio Blanco 3, 4 , Elisabeth Castellanos 4, 5 , Isabel Bielsa 1, 2
Affiliation  

Linear Cowden nevus, also known as linear PTEN nevus, is a type of epidermal nevus, first described in 2007, which is seen in patients with PTEN hamartoma tumor syndrome. It is considered to be a type 2 form of segmental mosaicism, and we suggest that it has certain clinical features that distinguish it from epidermal nevi seen in similar conditions, such as Proteus syndrome. We present a case of linear Cowden nevus in a 4-year-old boy and review the literature.

中文翻译:

疣状表皮痣是 Cowden 综合征 2 型马赛克 PTEN 突变的表现

线状考登痣,又称线状 PTEN 痣,是表皮痣的一种,于 2007 年首次描述,见于 PTEN 错构瘤综合征患者。它被认为是节段性嵌合体的 2 型形式,我们认为它具有某些临床特征,可将其与类似情况下的表皮痣区分开来,例如变形杆菌综合征。我们介绍了一例 4 岁男孩的线状考登痣,并回顾了文献。
更新日期:2022-09-24
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