Frontiers in Veterinary Science ( IF 2.6 ) Pub Date : 2022-09-23 , DOI: 10.3389/fvets.2022.970818 Lan Wu 1 , Youjun Li 1 , Xueyang Chen 1 , Yuxin Yang 1 , Chun Fang 1 , Yufang Gu 1 , Jing Liu 1 , Xiongyan Liang 1 , Yuying Yang 1
A strain of avian leukosis virus (ALV) belonging to a new envelope subgroup J (ALV-J) emerged in 1988 as a new subgroup of ALV and spread rapidly throughout the world. Due to the infection and spread of ALV-J, the global poultry industry experienced a significant loss. Although the disease had been prevented and controlled effectively by culling domestic chickens in the infected zone, a few field cases of ALV-J infection were reported in China in recent years. This study was conducted to characterize the genome and analyze the lesions and histopathology of the ALV-J strain named HB2020, which was isolated from layer chickens in Hubei Province, China. The full-length proviral genome sequence analysis of ALV-J HB2020 revealed that it was a recombinant strain of ev-1 and HPRS-103 in the