The authors of this study evaluated infant and parent outcomes at 12 and 24 months after a clinician-supported, web-based early intervention for preterm infants. OBJECTIVE To examine the efficacy of a clinician-supported, web-based intervention delivered over the first year after birth compared with standard care in children born after <34 weeks' gestation, on child development at 24 months corrected age (CA), parental mental health, and the parent-child relationship at 24 months. METHODS We randomly allocated 103 preterm infants to clinician-supported, web-based intervention (n = 50) or standard care control (n = 53) groups. At 24 months CA, child cognitive, language, motor, social-emotional development, and the parent-child relationship were assessed. Parental mental health and quality of life were assessed at 12 and 24 months CA. RESULTS At 24 months, child development, maternal mental health, and maternal quality of life were similar for the intervention and control groups. There was some evidence that mothers in the intervention group had lower odds of being in the elevated category for depression at 12 months (odds ratio: 0.19; 95% confidence interval [CI]: 0.04-0.90; P = .04). Scores were higher in the intervention group for child responsiveness (mean difference: 0.57; 95% CI: 0.03-1.11; P = .04), child involvement (mean difference: 0.61; 95% CI: 0.09-1.13; P = .02), and maternal structuring (mean difference: 0.72; 95% CI: 0.22-1.21; P = .01) during the parent-infant interaction at 24 months. CONCLUSIONS This study provides preliminary evidence that a clinician-supported, web-based early intervention program for preterm infants had a positive effect on the parent-child relationship and maternal mental health immediately after the intervention but potentially little effect on child development.

中文翻译：

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临床医生支持的基于网络的干预后 24 个月的早产儿结局。

本研究的作者在临床医生支持的基于网络的早产儿早期干预后 12 个月和 24 个月评估了婴儿和父母的结果。目的 比较临床医生支持的、基于网络的干预在出生后第一年与标准护理相比，在小于 34 周妊娠后出生的儿童、24 个月校正年龄 (CA) 的儿童发育、父母心理健康状况，以及 24 个月时的亲子关系。方法 我们将 103 名早产儿随机分配到临床医生支持的基于网络的干预组 (n = 50) 或标准护理控制组 (n = 53)。在 CA 24 个月时，评估了儿童的认知、语言、运动、社交情绪发展和亲子关系。在 CA 12 个月和 24 个月时评估父母的心理健康和生活质量。结果 在 24 个月时，干预组和对照组的儿童发育、母亲心理健康和母亲生活质量相似。有证据表明，干预组的母亲在 12 个月时患抑郁症的几率较低（优势比：0.19；95% 置信区间 [CI]：0.04-0.90；P = .04）。干预组儿童反应性（平均差：0.57；95% CI：0.03-1.11；P = .04）、儿童参与（平均差：0.61；95% CI：0.09-1.13；P = .02）得分较高)，以及 24 个月时亲子互动期间的母婴结构（平均差：0.72；95% CI：0.22-1.21；P = .01）。结论 本研究提供的初步证据表明，临床医生支持，