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Infections caused by Clostridium perfringens and Paeniclostridium sordellii after unsafe abortion
The Lancet Infectious Diseases ( IF 36.4 ) Pub Date : 2022-09-22 , DOI: 10.1016/s1473-3099(22)00590-4
David M Aronoff 1 , Jeanne M Marrazzo 2
Affiliation  

After the legalisation of abortion in the USA in 1973, the risk of infectious morbidity and mortality from this procedure notably decreased. With increasingly restrictive legislation targeting access to safe abortion services, reviewing infectious complications of unsafe pregnancy termination is crucial, particularly the diagnosis and management of life-threatening clostridial (and related anaerobic bacterial) infections that can complicate unsafe abortion. This Review deals with two especially devastating infections that are well-documented causes of septic abortion: the anaerobic, spore-forming pathogens Clostridium perfringens and Paeniclostridium sordellii. We seek to familiarise the reader with these bacteria, the clinical syndromes they can cause (with a focus on toxic shock syndrome), and provide a review of diagnosis and treatment options.



中文翻译:

不安全流产后产气荚膜梭状芽胞杆菌和索氏梭状芽胞杆菌感染

1973 年美国堕胎合法化后,该程序的感染发病率和死亡率风险显着降低。随着针对获得安全流产服务的越来越严格的立法,审查不安全终止妊娠的感染性并发症至关重要,特别是诊断和管理可能使不安全流产复杂化的危及生命的梭菌(和相关厌氧菌)感染。这篇综述涉及两种特别具有破坏性的感染,它们是有据可查的败血性流产原因:厌氧、形成孢子的病原体产气荚膜梭菌索德梭菌. 我们试图让读者熟悉这些细菌、它们可能引起的临床综合征(重点是中毒性休克综合征),并提供诊断和治疗方案的回顾。

更新日期:2022-09-22
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