Focal dermal hypoplasia (FDH), or Goltz syndrome, is a rare genodermatosis affecting tissues of mesodermal and ectodermal origin. The characteristic skin changes have been reported to symptomatically flare in response to certain triggers as well as to progress over time in some cases. We present the case of a 5-year-old girl with cutaneous flaring and progression of FDH in the setting of septic shock. This case adds to the growing body of literature on both flaring and progression of the cutaneous manifestations of FDH.

中文翻译：

---

急性疾病期间局灶性真皮发育不全的进展和扩张

局灶性真皮发育不全 (FDH) 或 Goltz 综合征是一种罕见的遗传性皮肤病，影响中胚层和外胚层来源的组织。据报道，特征性皮肤变化会因某些触发因素而出现症状性发作，并且在某些情况下会随着时间的推移而进展。我们介绍了一名 5 岁女孩在感染性休克的情况下出现皮肤红肿和 FDH 进展的病例。该病例增加了越来越多关于 FDH 皮肤表现的发作和进展的文献。