Cordyceps militaris has long been used in Eastern medicine for alleviating fatigue and as an immunostimulant. The present study aimed to determine the content of biologically active substances (bioelements and organic compounds), the total phenolic content, and the antioxidant activity of fruiting bodies (commercially available and self-cultivated), mycelia, and two food supplements. The results show that substrate composition and cultivation method had an influence on the properties of mushroom materials. An important aspect of the study is the estimation of the content of bioactive substances present after extraction into digestive juices in the artificial gastrointestinal tract model, which can allow for determining the amount of these substances that is potentially bioavailable for the human body. The best results for cordycepin (81.4 mg/100 g d.w.) and lovastatin (53.6 mg/100 g d.w.) were achieved for commercially available food supplements. Furthermore, after digestion in artificial intestinal juice, the highest amount of cordycepin was determined in the fruiting bodies from commercially obtained (25.9 mg/100 g d.w.) and self-cultivated mushroom (25.8 mg/100 g d.w.). In conclusion, the mycelium and fruiting bodies of C. militaris are ideal food supplements and pharmaceutical agents and can serve as a good source of prohealth substances potentially bioavailable for humans.

中文翻译：

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蛹虫草——果体、菌丝体和补充剂：日常饮食的重要组成部分

蛹虫草长期以来一直在东方医学中用于缓解疲劳和作为免疫刺激剂。本研究旨在确定子实体（市售和自培）、菌丝体和两种食品补充剂的生物活性物质（生物元素和有机化合物）含量、总酚含量和抗氧化活性。结果表明，底物组成和栽培方法对蘑菇材料的性质有影响。该研究的一个重要方面是在人工胃肠道模型中估计提取到消化液中后存在的生物活性物质的含量，这可以确定这些物质对人体潜在的生物利用度。虫草素的最佳结果（81.4 mg/100 g dw ) 和洛伐他汀 (53.6 mg/100 g dw) 用于市售食品补充剂。此外，在人工肠液中消化后，商业获得的（25.9 mg/100 g dw）和自培蘑菇（25.8 mg/100 g dw）的子实体中的虫草素含量最高。总之，菌丝体和子实体蛹虫草是理想的食品补充剂和药剂，可以作为人类潜在生物可利用的促健康物质的良好来源。