Periodontitis and peri-implantitis are common in the population worldwide. Periodontal diseases affect approximately 50% of adults, while mucositis affects 80% of patients with implants, turning into peri-implantitis at a rate varying from 28 to 58%. If standardized treatments for all degrees and variety of periodontal diseases are known and codified, a consensus on the treatment of peri-implantitis still has to be found. Photodynamic therapy (PDT) has been used successfully in the medical field and was recently introduced as supportive therapy in dentistry. This paper reviews the results on 20 patients, 10 affected by periodontal disease (grades II to III) and 10 by peri-implantitis. Application of 5% 5-aminolevulinic acid gel (ALAD), as a support of causal therapy, in periodontal pockets and areas of peri-implantitis favored the maintenance of severely compromised teeth and significantly improved compromised implant conditions. Between baseline and 6 months, all teeth and implants remained functional. All patients confirmed that the scaling and root planning (SRP)+ALAD-PDT was not painful, and all perceived a benefit after the treatment at all timing points. For periodontal patients, a significant decrease in PPD after 3 (p < 0.001) and 6 months after SRP+ALAD-PDT respect baseline values were observed. For the implant patients, the SRP+ALAD-PDT was correlated to a decrease in PPD and BOP, and a slight increase in the number of exposed threads. However, the results were statistically significant only for PPD (p < 0.001).

中文翻译：

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5-氨基乙酰丙酸光动力疗法治疗牙周炎和种植体周围炎：20 例患者的回顾性分析

牙周炎和种植体周围炎在全世界人群中很常见。牙周病影响大约 50% 的成年人，而粘膜炎影响 80% 的种植体患者，并以 28% 至 58% 不等的比率转变为种植体周围炎。如果各种程度和各种牙周病的标准化治疗是已知的和成文的，那么仍然需要找到关于种植体周围炎治疗的共识。光动力疗法 (PDT) 已成功应用于医学领域，最近作为支持疗法引入牙科。本文回顾了 20 名患者的结果，其中 10 名患有牙周病（II 至 III 级），10 名患有种植体周围炎。应用 5% 5-氨基乙酰丙酸凝胶 (ALAD) 作为对症治疗的支持，在牙周袋和种植体周围炎区域有利于维护严重受损的牙齿，并显着改善受损的种植体状况。在基线和 6 个月之间，所有牙齿和种植体都保持功能。所有患者均确认刮治和根面平整 (SRP) + ALAD-PDT 没有疼痛，并且在所有时间点治疗后都感到获益。对于牙周病患者，3 (p < 0.001) 和 6 个月后观察到 SRP+ALAD-PDT 方面的基线值。对于种植体患者，SRP+ALAD-PDT 与 PPD 和 BOP 的降低以及暴露螺纹数量的轻微增加相关。然而，结果仅对 PPD 具有统计学意义 ( p < 0.001)。