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Divergence of mutational signatures in association with breast cancer subtype
Molecular Carcinogenesis ( IF 3.0 ) Pub Date : 2022-09-16 , DOI: 10.1002/mc.23461
Gili Perry 1 , Maya Dadiani 1, 2 , Smadar Kahana-Edwin 1 , Anya Pavlovski 3 , Barak Markus 4 , Gil Hornung 4 , Nora Balint-Lahat 3 , Ady Yosepovich 3 , Goni Hout-Siloni 1 , Jasmine Jacob-Hirsch 1 , Miri Sklair-Levy 5, 6 , Eitan Friedman 6, 7 , Iris Barshack 3, 6 , Bella Kaufman 6, 8 , Einav Nili Gal-Yam 8, 9 , Shani Paluch-Shimon 8, 10
Affiliation  

Abnormal molecular processes occurring throughout the genome leave distinct somatic mutational patterns termed mutational signatures. Exploring the associations between mutational signatures and clinicopathological features can unravel potential mechanisms driving tumorigenic processes.

中文翻译:

与乳腺癌亚型相关的突变特征的差异

整个基因组中发生的异常分子过程会留下不同的体细胞突变模式,称为突变特征。探索突变特征与临床病理学特征之间的关联可以揭示驱动致瘤过程的潜在机制。
更新日期:2022-09-16
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