Steatosis, HBV-related HCC, cirrhosis, and HBsAg seroclearance: A systematic review and meta-analysis,Hepatology

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Steatosis, HBV-related HCC, cirrhosis, and HBsAg seroclearance: A systematic review and meta-analysis
Hepatology ( IF 12.9 ) Pub Date : 2022-09-15 , DOI: 10.1002/hep.32792
Xianhua Mao ₁ , Ka Shing Cheung _{1,

2} , Chengzhi Peng ₃ , Lung-Yi Mak _{1,

4} , Ho Ming Cheng ₁ , James Fung _{1,

4} , Noam Peleg _{5,

6} , Howard H-W Leung ₇ , Rajneesh Kumar _{8,

9} , Jeong-Hoon Lee ₁₀ , Amir Shlomai ₁₁ , Man-Fung Yuen _{1,

4} , Wai-Kay Seto _{1,

2,

4}

Affiliation

Department of Medicine, School of Clinical Medicine , The University of Hong Kong , Hong Kong.
Department of Medicine , The University of Hong Kong-Shenzhen Hospital , Shenzhen , China.
Li Ka Shing Faculty of Medicine , The University of Hong Kong , Hong Kong.
State Key Laboratory of Liver Research , The University of Hong Kong , Hong Kong.
Division of Gastroenterology , Rabin Medical Center , Petach Tikva , Israel.
Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel.
Department of Anatomical and Cellular Pathology , The Chinese University of Hong Kong , Hong Kong.
Department of Gastroenterology and Hepatology , Singapore General Hospital , Singapore.
Duke-NUS Graduate Medical School , Singapore.
Department of Internal Medicine and Liver Research Institute , Seoul National University College of Medicine , Seoul , Republic of Korea.
Department of Medicine D and The Liver Institute, Rabin Medical Center , Beilinson Hospital, Petah-Tikva and the Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel.

NAFLD and chronic hepatitis B (CHB) infection are common etiologies of HCC. The impact of hepatic steatosis on HCC in CHB, as well as its relationship with the development of cirrhosis, fibrosis, and HBsAg seroclearance, remains controversial.

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