Long-lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8⁺ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL-15/IL-15R heterodimer (15HD)-expressing myeloid cells. Nonmyeloid hepatic stellate cells (HSCs) also express 15HD, but their role in maintaining MemCD8TC homeostasis is unknown.

中文翻译：

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小鼠体内的 CD8+ T 细胞记忆由肝星状细胞维持

持久的免疫记忆是疫苗接种的最终目标。记忆 CD8 ⁺细胞毒性 T 细胞 (MemCD8TCs) 的稳态维持被认为是由表达 IL-15/IL-15R 异二聚体 (15HD) 的骨髓细胞介导的。非髓样肝星状细胞 (HSC) 也表达 15HD，但它们在维持 MemCD8TC 稳态中的作用尚不清楚。