Urine is a viral antigen reservoir in hepatitis E virus infection,Hepatology

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Urine is a viral antigen reservoir in hepatitis E virus infection
Hepatology ( IF 12.9 ) Pub Date : 2022-09-15 , DOI: 10.1002/hep.32745
Dong Ying ₁ , Qiyu He ₂ , Weikun Tian ₁ , Yanling Chen ₁ , Xiaoping Zhang ₁ , Siling Wang ₁ , Chang Liu ₁ , Zihao Chen ₁ , Yu Liu ₃ , Lijuan Fu ₄ , Li Yan ₃ , Ling Wang ₂ , Zimin Tang _{1,

5} , Lin Wang ₂ , Zizheng Zheng ₁ , Ningshao Xia ₁

Affiliation

HEV ORF2 antigen (Ag) in serum has become a tool for diagnosing current HEV infection. Particularly, urinary shedding of HEV Ag has been gaining increasing interest. We aim to uncover the origin, antigenicity, diagnostic performance, and diagnostic significance of Ag in urine in HEV infection.

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