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Impact of Physiologically Relevant Genistein Exposure at Different Time Windows on Puberty Onset and Neuroendocrine Function in Female Rats
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2022-09-15 , DOI: 10.1002/mnfr.202200486
Jingyuan Xiong 1 , Ye Tian 1 , Guochen Ma 1 , Xiaoyu Wang 2 , Shufang Shan 2 , Guo Cheng 2
Affiliation  

Puberty timing, critical for adulthood wellbeing, is influenced by the environment, life-style, and diets. However, differential puberty-interfering effects of soy and soy isoflavone are observed in both epidemiological and toxicological studies. Additionally, their impact on neuroendocrine function at various pre-pubertal developmental windows is unclear.

中文翻译:

不同时间窗生理相关染料木黄酮暴露对雌性大鼠青春期开始和神经内分泌功能的影响

青春期时间对成年期的幸福至关重要,受环境、生活方式和饮食的影响。然而,在流行病学和毒理学研究中都观察到了大豆和大豆异黄酮的不同青春期干扰作用。此外,它们对各种青春期前发育窗口的神经内分泌功能的影响尚不清楚。
更新日期:2022-09-15
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