Capillary rarefaction during bed rest is proportionally less than fibre atrophy and loss of oxidative capacity,Journal of Cachexia, Sarcopenia and Muscle

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Capillary rarefaction during bed rest is proportionally less than fibre atrophy and loss of oxidative capacity
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2022-09-13 , DOI: 10.1002/jcsm.13072
Paul William Hendrickse _{1,

2} , Rob C I Wüst ₃ , Bergita Ganse ₄ , Ifigeneia Giakoumaki _{1,

5} , Jörn Rittweger _{6,

7} , Alessandra Bosutti ₈ , Hans Degens _{1,

9}

Affiliation

Muscle disuse from bed rest or spaceflight results in losses in muscle mass, strength and oxidative capacity. Capillary rarefaction may contribute to muscle atrophy and the reduction in oxidative capacity during bed rest. Artificial gravity may attenuate the negative effects of long-term space missions or bed rest.

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