Coronavirus disease 2019 (COVID-19) is a communicable disease triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged as leading cause of death from a single infectious agent globally. Despite of rigorous protective measures, availability of multiple vaccines and with few approved therapeutics, the virus effect on the humankind throughout the world is perennial. COVID-19 has become the most urgent health concern with emergence of new challenging variants which outnumbered all other health issues and ensued in overwhelming number of reported deaths. In this unprecedented period of COVID-19 pandemic, scientists work round the clock for rapid development of efficient vaccines for prevention of infection and effective therapeutics for treatment. Here, we report the status of COVID-19 and highlight the ongoing research and development of vaccines and therapeutic strategies. It is necessary to know the present situation and available options to fight against the COVID-19 pandemic.

2019 年冠状病毒病 (COVID-19) 是一种由严重急性呼吸系统综合症冠状病毒 2 (SARS-CoV-2) 引发的传染病，已成为全球单一传染原的主要死因。尽管采取了严格的保护措施、多种疫苗的可用性以及几乎没有批准的治疗方法，但病毒对全世界人类的影响是长期存在的。随着新的具有挑战性的变种的出现，COVID-19 已成为最紧迫的健康问题，这些变种的数量超过所有其他健康问题，并导致大量死亡报告。在这个史无前例的 COVID-19 大流行时期，科学家们夜以继日地工作，以快速开发用于预防感染的有效疫苗和用于治疗的有效疗法。这里，我们报告了 COVID-19 的状况，并强调了正在进行的疫苗和治疗策略的研究和开发。有必要了解目前的情况和可用的选项来对抗 COVID-19 大流行。