Mitral regurgitation in the neonatal period is relatively rare. It can be secondary to a congenital malformation of the valve apparatus or mitral valve dysfunction and deformation secondary to myocardial dysfunction or volume load of the left ventricle. Less commonly, it can be due to coronary artery abnormalities leading to mitral valve papillary muscle ischaemia and subsequent dysfunction. Such coronary artery abnormalities include anomalous left coronary artery from pulmonary artery, left main coronary artery atresia, or a thromboembolic phenomenon. In this study, we describe a newborn with a dysplastic aortic valve causing obstruction of the os of the left coronary artery leading to progressive mitral insufficiency.

新生儿期二尖瓣反流相对少见。它可以继发于瓣膜装置的先天性畸形或二尖瓣功能障碍以及继发于心肌功能障碍或左心室容量负荷的变形。不太常见的是，它可能是由于冠状动脉异常导致二尖瓣乳头肌缺血和随后的功能障碍。这种冠状动脉异常包括从肺动脉异常左冠状动脉、左冠状动脉主干闭锁或血栓栓塞现象。在这项研究中，我们描述了一名新生儿，其主动脉瓣发育不良导致左冠状动脉口阻塞，导致进行性二尖瓣关闭不全。