Variation exists in the timing of surgery for balanced complete atrioventricular septal defect repair. We sought to explore associations between timing of repair and resource utilisation and clinical outcomes in the first year of life.

In this retrospective single-centre cohort study, we included patients who underwent complete atrioventricular septal defect repair between 2005 and 2019. Patients with left or right ventricular outflow tract obstruction and major non-cardiac comorbidities (except trisomy 21) were excluded. The primary outcome was days alive and out of the hospital in the first year of life.

Included were 79 infants, divided into tertiles based on age at surgery (1st = 46 to 137 days, 2nd = 140 – 176 days, 3rd = 178 – 316 days). There were no significant differences among age tertiles for days alive and out of the hospital in the first year of life by univariable analysis (tertile 1, median 351 days; tertile 2, 348 days; tertile 3, 354 days; p = 0.22). No patients died. Fewer post-operative ICU days were used in the oldest tertile relative to the youngest, but days of mechanical ventilation and hospitalisation were similar. Clinical outcomes after repair and resource utilisation in the first year of life were similar for unplanned cardiac reinterventions, outpatient cardiology clinic visits, and weight-for-age z-score at 1 year.

Age at complete atrioventricular septal defect repair is not associated with important differences in clinical outcomes or resource utilisation in the first year of life.

平衡性完全房室间隔缺损修复手术的时机存在差异。我们试图探索修复时​​间和资源利用与生命第一年临床结果之间的关联。

在这项回顾性单中心队列研究中，我们纳入了 2005 年至 2019 年间接受完全房室间隔缺损修复的患者。排除了左或右心室流出道梗阻和主要非心脏合并症（21 三体综合征除外）的患者。主要结果是出生后第一年的存活天数和出院天数。

包括 79 名婴儿，根据手术年龄分为三组（第 1 = 46 至 137 天，第 2 = 140 – 176 天，第 3 = 178 – 316 天）。通过单变量分析，出生后第一年存活天数和出院天数的年龄三分位数之间没有显着差异（三分位数 1，中位数 351 天；三分位数 2，348 天；三分位数 3，354 天；p = 0.22）。没有患者死亡。与最年轻的三分位数相比，年龄最大的三分位数使用术后 ICU 天数更少，但机械通气和住院天数相似。修复后的临床结果和生命第一年的资源利用在计划外心脏再介入、门诊心脏病学门诊就诊和 1 年年龄别体重 z 评分方面相似。

完全修复房室间隔缺损的年龄与生命第一年的临床结果或资源利用的重要差异无关。