individual identification of changes in total (ΔcHbi), oxygenated (Δo2Hbi), and deoxygenated (ΔHHbi) hemoglobin spectral absorptions. Variations in these parameters from baseline help identify the underlying mechanisms of cerebral desaturation. This case series represents the first preliminary description of Δo2Hbi, ΔHHbi, and ΔcHbi variations in 10 cardiac surgical settings. Hemoglobin spectral absorption changes can be classified according to 3 distinct variations of cerebral desaturation. Reduced cerebral oxygen content or increased cerebral metabolism without major blood flow changes is reflected by decreased Δo2Hbi, unchanged ΔcHbi, and increased ΔHHbi Reduced cerebral arterial blood flow is suggested by decreased Δo2Hbi and ΔcHbi, with variable ΔHHbi. Finally, acute cerebral congestion may be suspected with increased ΔHHbi and ΔcHbi with unchanged Δo2Hbi. Cerebral desaturation can also result from mixed mechanisms reflected by variable combination of those 3 patterns. Normal cerebral saturation can occur, where reduced cerebral oxygen content such as anemia is balanced by a reduction in cerebral oxygen consumption such as during hypothermia. A summative algorithm using rSo2, Δo2Hbi, ΔHHbi, and ΔcHbi is proposed. Further explorations involving more patients should be performed to establish the potential role and limitations of monitoring hemoglobin spectral absorption signals....

中文翻译：

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在心脏手术中使用无创氧合血红蛋白、脱氧血红蛋白和总血红蛋白早期检测和纠正大脑去饱和：一个案例系列

总血红蛋白 (ΔcHbi)、含氧 (Δo2Hbi) 和脱氧 (ΔHHbi) 血红蛋白光谱吸收变化的个体识别。这些参数相对于基线的变化有助于确定大脑去饱和的潜在机制。该病例系列首次初步描述了 10 种心脏手术环境中的 Δo2Hbi、ΔHHbi 和 ΔcHbi 变异。血红蛋白光谱吸收变化可根据大脑去饱和的 3 种不同变化进行分类。Δo2Hbi 降低、ΔcHbi 不变和 ΔHHbi 升高反映脑氧含量降低或脑代谢增加而无主要血流变化 Δo2Hbi 和 ΔcHbi 降低表明脑动脉血流减少，ΔHHbi 可变。最后，ΔHHbi 和 ΔcHbi 增加而 Δo2Hbi 不变时，可能怀疑急性脑充血。大脑去饱和也可能由这 3 种模式的可变组合所反映的混合机制引起。可以发生正常的脑饱和，其中脑氧含量降低（例如贫血）通过脑氧消耗减少（例如在体温过低期间）来平衡。提出了一种使用 rSo2、Δo2Hbi、ΔHHbi 和 ΔcHbi 的求和算法。应进行涉及更多患者的进一步探索，以确定监测血红蛋白光谱吸收信号的潜在作用和局限性…… 大脑含氧量减少（如贫血）与大脑耗氧量减少（如体温过低期间）相平衡。提出了一种使用 rSo2、Δo2Hbi、ΔHHbi 和 ΔcHbi 的求和算法。应进行涉及更多患者的进一步探索，以确定监测血红蛋白光谱吸收信号的潜在作用和局限性…… 大脑含氧量减少（如贫血）与大脑耗氧量减少（如体温过低期间）相平衡。提出了一种使用 rSo2、Δo2Hbi、ΔHHbi 和 ΔcHbi 的求和算法。应进行涉及更多患者的进一步探索，以确定监测血红蛋白光谱吸收信号的潜在作用和局限性……